Information Analysis of Dynamic Synapses
It was recently shown that fast synaptic dynamics strongly influences the information transmission through neocortical synapses. In particular, transmission of the firing rates in depressing synapses is limited to low frequencies. We applied the methods of Shannon's information theory to analyze the ability of dynamic synapses to transmit the information about exact patterns of spikes in the presynaptic neuron. The results showed an interesting interplay between rate and temporal coding and allowed to compute the length of the 'spike packets' which are effectively transmitted to the postsynaptic neuron. We used intracellular recordings from connected pairs of neocortical neurons to test the conclusions of theoretical analysis.